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and in limited contact with water ( max = 340342 nm, = 5355 nm, q = 0.3, = 4.4 ns) ( 2.12.4 Quenching of fluorescence A very promising spectroscopic technique for evaluation of solvent accessibility of aromatic residues in a protein involves the quenching of their intrinsic fluorescence by the addition of various low molecular weight agents (Lehrer, 1971

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Originally developed as a GLP-1 receptor agonist for type 2 diabetes and obesity, semaglutide has recently attracted attention for its potential to modulate neural reward pathways

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