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Los resultados clnicos y preclnicos respaldan su papel en una nueva era teraputica que apunta hacia una visin integradora del metabolismo, en la cual el tratamiento se orienta no solo a la glucosa, sino a la mejora del estado metablico global del paciente

doi.org/10.3389/fphar.2021.627533 Chang, C

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The tumor suppressor VHL can interact with PKC and prevent its binding to IGF-IR, thereby abrogating IGF-IR-PKC signaling [62]