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Actin-sorting nexin 27 (SNX27)-retromer complex mediates rapid parathyroid hormone receptor recycling

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In the pivotal, phase 3, placebo-controlled RESPONSE trial (NCT04620733), seladelpar, a novel delpar (selective PPAR-delta agonist), led to a significantly higher percentage of PBC patients achieving the composite biochemical endpoint (ALP 0 U/L from baseline) and safety by baseline ALP subgroup were also evaluated

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Protein-rich meals produce a stronger GLP-1 response than carbohydrate-heavy meals of the same calorie count