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doi: 10.1016/j.freeradbiomed.2016.08.028

Unless an exception in 21 CFR 1271.15 applies, such products are regulated as drugs, devices, and/or biological products under the FD&C Act and/or the PHS Act and are subject to additional regulation, including applicable premarket review and approval

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Both medications affect appetite and metabolism through different pathways, but their combined use raises cardiovascular concerns that most evidence-based guidelines do not support

Loperamide, known as Immodium, is an opioid drug, meaning that its part of the same family of substances as prescription painkillers and heroin