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J Endocrinol Invest 41:583590

Arbutin, the b-D-glucopyranoside derivative of hydroquinone, is a naturally occurring plant-derived compound found in the dried leaves of a number of different plant species including, bearberry (Arctostaphylos uva-ursi), blueberry, cranberry, and pear trees

Introduction Pregnancy is characterized by significant physiological changes resulting in various symptoms, such as nausea, vomiting, heartburn, and constipation

Complications Endometriosis increases the chance for irritable bowel syndrome by more than two folds compared to women without endometriosis [28]