Our novel NNMT inhibitors display excellent physical chemical properties (e.g., membrane permeability), selectivity, and cellular inhibitory activity against NNMT, concomitantly enhancing the levels of the cofactors SAM and NAD + that independently regulate cellular energy metabolism and epigenetic modifications
Rather than targeting appetite or hormones, MOTS-c primarily affects cellular metabolism
Vitamin B12 shots are ideal for individuals who have dietary restrictions, such as vegans or vegetarians, experience digestive issues that affect nutrient absorption, or suffer from conditions like pernicious anemia
(Intrinsic factor is made by cells in the lining of the stomach and is needed for vitamin B12 to be absorbed.) Pernicious anaemia is the most common cause of B12 deficiency in Ireland
Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet
