All participants signed a written informed consent form (supplementary materials 710), and the protocol was reviewed and approved by the Institutional Ethics Committee of the First Affiliated Hospital of Hebei North University (approval no
It is important to note that the frequency of fatigue varies between different GLP-1 products and doses, with higher rates typically seen with the weight management doses compared to the lower doses used for diabetes treatment
NAD+ supplements, therefore, are taken with the intention of replenishing dwindling NAD+ levels, potentially offering benefits such as: Improved energy production Enhanced cognitive function Cellular repair and protection Potential anti-ageing effects NAD+ supplements can come in various forms, including oral capsules, sublingual tablets, injections, or IV drips
The GSH detection assay is based on the conversion of a luciferin derivative into luciferin in the presence of GSH
Immunoblotting was performed with specific primary antibodies (see ESM Methods)