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Smith, D., M

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For experiments visualising axonal projections from brainstem PPG neurons PPG-YFP mice and PPG-Cre mice were crossed, and their YFP- and Cre-positive offspring ( n = 3) injected bilaterally with AAV2-Ef1a-DIO-tdTomato (0.25 l/injection

Supporting our cytochrome c assays, we confirmed no change in mitochondrial outer membrane permeabilization (MOMP) in cells surviving 5FU treatment (compared to the dimethyl sulfoxide group), and no increase in mitochondrial apoptotic priming based on BH3-profiling 15,16 induced by 5FU treatment (Extended Data Fig