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In addition, the maximum AEF0117 dose administered was selected so that the plasma exposures for AEF0117 in humans would not exceed the mean AUC of 41,611 ng h ml 1 and/or mean C max of 4,361 ng ml 1 , corresponding to the highest dose tested in animals without toxicity at the time of the study

In laboratory research, AOD 9604 is used to explore pathways involved in fat breakdown (lipolysis), fat storage (lipogenesis), and energy use, without the broader endocrine activity associated with full-length growth hormone