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TSH-R stimulation leads to adenylyl cyclase activation and leveling up of the intracellular levels of cAMP which subsequently leads to protein kinase A (PKA) activation

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SS-31 (Elamipretide) What It Is: A "mitochondrial rescue" agent that protects and optimizes the function of our cellular power plants

It inhibits the production of pro-inflammatory cytokines (TNF-alpha, IL-6, IL-12) and modulates macrophage polarization towards the M2 phenotype (reparative/anti-inflammatory)

Most dermatologists recommend an initial intensive phase (1224 weeks) followed by less frequent maintenance sessions