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Over many draws, the remaining solution becomes slightly more concentrated as proportionally more water evaporates through the tiny stopper channels

While these findings highlight promising biological activity, it is important to emphasize that current evidence is derived primarily from experimental animal models

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Potential CNS Access : Some research suggests nasal administration may facilitate direct transport to the central nervous system via olfactory and trigeminal nerve pathways, though this remains an area of ongoing investigation [5]

The remaining author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest