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Ann Intern Med 174(11):15281541

[PubMed] [Google Scholar] Gwinn W

However, side effects such as constipation and slowed digestion may increase flare risk in susceptible individuals

Early-stage research suggests intranasal dihexa may achieve therapeutic CNS concentrations with minimal systemic exposure, potentially extending the effective half life at the target site (hippocampus) while reducing plasma half life

As such, the choice between Mounjaro and Ozempic for weight loss should be based on a comprehensive evaluation by a healthcare provider, considering the individuals overall health, existing conditions, and specific weight loss goals