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Our results show that after 24 hr treatment, GHK attenuates U937 cell proliferation at 20 nM while GHK-PEG attenuates cell proliferation at 10 and 20 nM ( Figure 3 )

109, 110 Acute or chronic treatment with antioxidants or superoxide dismutase not only improved endothelial dysfunction but also markedly reduced blood pressure, indicating the potential role of ROS in the initiation and maintenance of hypertension

Recently studies have reported the role of iron accumulation and ferroptosis in bone loss

Proteomics 19(2122):e1800486 Cassago A, Ferreira AP, Ferreira IM et al (2012) Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism