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This risk is heightened by genetic variants such as the OATP1B1 R57Q polymorphism, which impairs drug transport and can lead to systemic toxicity (62, 63)

Prescription proton pump inhibitors (omeprazole, pantoprazole) are also compatible with tirzepatide therapy

Clerte, M

Cystine limitation induced the expression of AARE-containing genes in the ISR, which are involved in amino acid metabolism ( SLC7A11 , SLC7A1 and SLC38A2 ) and cell survival ( TRIB3 ) (Fig

Study 8 was a 72-week trial that enrolled 1,407 patients with obesity (BMI greater than or equal to 30 kg/m2), patients with type 2 diabetes mellitus were excluded