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The key difference lies in the reduced form of glutathione, which is more bioavailable and effective at neutralizing free radicals

The powder leaf sample (0.1 g) was homogenized with 1.5 mL of 1% Trichloroacetic acid (TCA) and the extract was centrifuged at 10,000 g at 4 C for 10 min

7 , 8 , 9 , 10 , 11 Taking that into consideration, evidence supporting the administration of antioxidants to mitigate OA aggressiveness is slowly beginning to rise, yet additional clarification of their protective mechanisms in joint tissues is still desirable in order to further reveal potential benefit to patients

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Hal tersebut terjadi karena glutathione menekan aktivitas enzim tirosinase yang berperan dalam pembentukan melanin, sehingga kadar melanin lebih rendah dan membuat kulit tampak cerah