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In addition, the 20% reduced risk for MACE seen in the SELECT trial of semaglutide (Wegovy, Novo Nordisk) was the same in patients in the lowest quartile of weight loss and the highest, he said

doi: 10.1016/S0305-4179(03)00004-4

This finding suggests that maximizing lean mass preservation through aggressive protein supplementation might partially blunt the weight loss efficacy of glucagon-containing compounds

Manchanda et al

Severe effects requiring emergency medical attention include severe abdominal pain, yellowing of skin or eyes, swelling of face or throat, difficulty breathing, fainting, or vision changes

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