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Key physiological features of the hypothalamo-pituitary-adrenal (HPA) axis are discussed, including the ultradian pulsatility of CRH, AVP and ACTH secretion, the circadian pattern of secretion, the negative feedback of cortisol on the HPA axis, the stress response, and the effects of aging and gender

Weight regain is common and often frustrating for patients who otherwise follow sound nutrition and exercise strategies

6,7 In June 2022, the TGA announced a subsequent shortage of dulaglutide

Over-the-counter remedies such as simeticone (for gas and bloating) or loperamide (for diarrhoea) can provide symptomatic relief, though patients should consult their GP or pharmacist before regular use

Consuming lentinula edodes (Shiitake) mushrooms daily improves human immunity: a randomized dietary intervention in healthy young adults