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Ethics declarations Ethics approval and consent to participate All animal experiments were conducted after approval from the Institutional Animal Care and Use Committee of the Tongji Medical College, Huazhong University of Science and Technology, and all procedures were in compliance with the relevant guidelines and regulations of the Chinese Council on Animal Care

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Individuals with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) are typically advised against using GLP-1 medications

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