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Prescribers are advised to: Review eGFR before initiating treatment and consult the relevant SmPC for renal-specific guidance Monitor renal function periodically during therapy, particularly in those with CKD, risk factors, or on nephroactive medicines Counsel patients on adequate hydration, especially during periods of illness or reduced oral intake Patients should always ensure their prescriber is aware of any kidney condition before starting any weight loss medication

These include the purchase of Ivax Corporation in 2006, Barr Pharmaceuticals in 2008 and Actavis Generics from Allergan in 2016

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Liposomal glutathione is often preferred because it is designed for higher bioavailability and cellular uptake