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By contrast, in immune and inflammatory responses, cytokines and/or bacterial lipopolysaccharide induce expression of the inducible form of NO synthase (NOS-2) leading to relatively slow, sustained and high level production of NO [13]

Immune stimulation function: The adjuvant can activate the differentiation, aggregation, and activation of APC and T cells

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Qureshi GA, Qureshi AA, Devrajani BR, Chippa MA, Syed SA