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Other Options May Be Preferable For People Who: Need Significant Medical Intervention: If you're dealing with obesity, type 2 diabetes, metabolic syndrome, or other serious health conditions, work with a healthcare provider

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Christofides, A., Konstantinidou, E., Jani, C

Wang L, Wang B, Gasek NS, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kim T, Langhi Prata LGP, Palmer AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Du W, Kshitiz KGA, Meves A, Tchkonia T, Kirkland JL, Robson P, Xu M (2022) Targeting p21(Cip1) highly expressing cells in adipose tissue alleviates insulin resistance in obesity

Lancet 401 , 15841594 (2023)