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Researchers also observed that approximately half of the nonessential amino acids required for protein synthesis in tumor cells are derived from glutamine using isotopic tracing methods [77]

Peroxisome proliferator-activated receptor alpha (PPAR) and its co-activator, peroxisome proliferator-activated receptor-gamma co-activator 1 alpha (PGC-1), function as upstream regulators of mitochondrial biogenesis and functionality

Some helpful bacteria in the stomach can accelerate the breakdown and creation of bioactive molecules with antioxidant capabilities from dietary antioxidants, such as polyphenols found in fruits and vegetables

As expected, the chemically reactive metabolites were much more cytotoxic than their respective precursors and displayed comparable and steep dose-dependent decreases in cell viability ( Figure 2 )

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