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High doses of alpha-lipoic acid are approved in Germany for the treatment of these symptoms

The combination of GLP-1 medication with reduced food intake creates a perfect storm for B-vitamin depletion

Additional information Supported by a grant from the Clintec Nutrition Division of Baxter Canada, Toronto, Ontario, Canada and the Medical Research Council of Canada (UI 14011) as well as Transcend Therapeutics, Cambridge MA and the Hospital for Sick Children Foundation (XG97-025), Toronto, Ontario, Canada, and Guigoz France

Telemedicine can be used to achieve the frequent patient contact crucial to weight management

Correlations between change in GLP-1 and change in bodyweight as well as change in IBS-SSS were assessed using visual inspection of scatterplots and by assessment of either Pearsons correlation, or if assumptions of normality and linearity were violated, by Spearmans rank-order correlation