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doi: 10.1016/j.intimp.2020.107362 253 DohertyEOaksZPerlA

International Regulations Other jurisdictions, like Canada, Australia, and the EU, have similar restrictions: In Canada , BPC157 is not approved by Health Canada and is not available through licensed pharmacies

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Cells were next lysed with 3 mL of lysis buffer (50 mM Tris-HCl pH 8.0, 150 mM NaCl, 1% NP-40, 10% glycerol) for 1 h at 4 o C

Further research is needed to elucidate these differences and to develop targeted therapeutic strategies that address the unique aspects of ferroptosis in each joint type