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doi: 10.1016/j.immuni.2019.08.001 22 DengDYanN

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Subsequent oxidative stress results in the age-dependent peroxidation of proteins, lipids, and nucleic acids by intracellular mitochondria, destruction of the mitochondrial membrane permeability, and reduction of oxygen respiratory chain activity, leading to an increase in the number of active oxygen species ( The nephroprotective action of HPL during menopause also deserves special consideration