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The most common side effects of B12 injections are mild and temporary, including pain, redness, or swelling at the injection site, mild nausea or diarrhea, headache, dizziness, and itching near the injection area

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In addition, B12 deficiency-associated fatigue is often accompanied by other symptoms such as numbness and tingling, cognitive impairment (memory and concentration problems), mood swings (depression), skin changes (pale skin), shortness of breath, or fast heart rate

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Therefore, the mitochondrial quality control system plays a critical role in the onset and progression of neurodegenerative diseases