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Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity
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STEP-3 (N=611, JAMA 2021) combined semaglutide 2.4 mg with intensive behavioral therapy and produced 16.0% mean weight loss at 68 weeks [6]
Data were extracted as follows: (1) species, number exposed to drug of interest, number of controls, timing and duration of exposure, dose (drug/kg/time-interval and equivalents to maximum recommended human dosage or clinical dosage), fetal effects of maternal GLP-1 agonist or SGLT2 inhibitor exposure, (2) species, number exposed to drug of interest, number of controls, timing and duration of exposure, dose (drug/kg/time-interval and equivalents to maximum recommended human dosage or clinical dosage), the transfer of GLP-1 agonist or SGLT2 inhibitor in maternal milk and the effect of exposure during lactation on the neonate
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