Estrogen, through its widespread receptors in brain areas of relevance to the addiction circuitry, can influence neurotransmission, lead researcher Erika Comasco, PhD, assistant professor in the Department of Womens and Childrens Health,Neuropsychopharmacology at Uppsala University in Sweden, told Healthline
On top of that, it has many other advantages
For example, a 2016 study involving 8,144 patients treated at 140 centers in 16 countries "did not show a significant increase in neuropsychiatric adverse events attributable to varenicline or bupropion relative to nicotine patch or placebo"
Like any institution, it's capable of being corrupt
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