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Due to activation of the mTOR pathway, which regulates cell growth [18], and modulation of the ATF6 pathway, affecting cytoskeletal structure [19], senescent cells often take on an enlarged and irregular morphology [18, 19]

doi: 10.1136/gutjnl-2018-317155 54 YuanZ.YinB.WeiD.YuanY.-R

Multiple comparisons of electrophysiological results were made using a one-way ANOVA followed by a Newman-Keuls post-hoc test with a level of significance set at p 0.05

Swank reported on 150 patients followed long-term, from 1949 to 1984

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