However, that the hepatotoxicity of APAP results from the production of the reactive metabolite N -acetyl- p -benzoquinoneimine (NAPQI/NABQI) that can deplete glutathione, react with cellular macromolecules, and initiate cell death, is now beyond dispute
Huang Q, Du J, Merriman C, Gong Z
Directed evolution has also been used to develop enzymes with new-to-nature functions
Zubkova EV, Robaire B (2004) Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat
U IM NI BT: Cng Ngh Liposomal c Quyn: m bo sinh kh dng cao v tng cng kh nng hp th Glutathione vo c th, gip hot cht pht huy hiu qu ti a