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Introduction Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder characterized by impaired social communication and interactions, as well as repetitive behavior and limited interests ( There are no clinical biomarkers for ASD because the disorder's etiology and pathogenesis are unknown ( However, ASD is a genetically diverse disorder
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Analysis of candidate cis-regulatory elements (cCREs) has shown that some diabetes-associated variants reduce chromatin accessibility at binding sites for transcription factors such as HNF1A and HNF4A, thereby impairing maintenance of a functional phenotype (Wang et al., 2023)
J Clin Endocrinol Metab 63: 492-498, 1986
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