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Our investigation identifies new potentially druggable locations in the receptor, expanding the existing repertoire of functionally relevant sites for the rational design of novel GLP-1R allosteric modulators based on the modulation of receptor-cholesterol interactions

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Compounded drugs are not approved by the Food and Drug Administration (FDA) and are not evaluated for safety or efficacy." The active ingredients used in compounded formulations may be sourced from FDA-registered facilities, but the finished compounded products themselves are not FDA-approved

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