BrightFocus Alzheimers Disease Research program has funded research into brain metabolism, inflammation, and novel therapeutic approaches that helped lay the groundwork for innovative discoveries like GLP-1s in Alzheimers disease
In SUSTAIN-6 trial similar effects in MACE risk reduction, glycemic control and hypoglycemia rates were observed in patients receiving 0.5 mg semaglutide once weekly and in those receiving 1 mg once weekly (43)
15 GLP-1s, technically glucagon-like peptide-1 receptor agonists, facilitate weight loss by slowing the movement of food through the gastrointestinal tract, increasing fullness, and suppressing appetite
Semaglutide (marketed under the brand name Wegovy) and liraglutide (Saxenda) did lead to weight loss, but it was significantly less at 15% and 8%, respectively
[DOI] [PubMed] [Google Scholar] 96.Linjawi S., Bode B.W., Chaykin L.B., Courreges J.P., Handelsman Y., Lehmann L.M