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That area is still developing, and findings vary across medications, populations, and study designs, so it is best treated as an emerging part of the picture rather than a settled explanation

This evidence gap means some caution remains appropriate despite the favorable safety signals available

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For peripheral nerve analysis, a 5-mm-long piece of tail 15 mm distal from the tail base was collected from each sacrificed animal, fixed in 4% formaldehyde in phosphate buffer (pH 7.4), decalcinated, and impregnated with 1% osmium tetroxide for a few days

(3) Thus, GHK-Cu is posited to act as a repair signal, capable of interacting with enzymes, ion channels, and cell-surface receptors, with reported downstream potential on gene expression