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3 : 3-(6-Methoxy-3,3-dimethyl-1-oxo-2,3,4,9-tetrahydro-1 H -xanthen-9-yl)-1 H -indole-2-carboxylic acid Compound 3 was obtained as an off-white amorphous solid with a melting point of 136.8137.8 C

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In addition, nutritional stress caused by a high fat high carbohydrate diet promotes oxidative stress, as evident by increased lipid peroxidation products, a diminished antioxidant system and decreased glutathione levels [82,83]