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Because the drug binds to GLP-1 receptors in the brain, regulating appetite and reducing food intake, the once-weekly subcutaneous injectable is sometimes prescribed off-label for weight loss

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Treating obesity would likely require a supervising physician with appropriate expertise (ideally family practice or internal medicine, not just a psychiatrist) (florida.public.law)

Other weight-loss drugs are currently in development or regulatory approval stages, including: Once-daily GLP-1 pill orforglipron (Eli Lilly), which, when taken alongside a healthy diet and exercise, resulted in a 7.5% weight loss over 72 weeks on the 6mg dose, 8.4% loss with 12mg of orforglipron, and 11.2% loss with 36mg of orforglipron, as compared with 2.1% loss with placebo (funded by Eli Lilly