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Intriguingly, DMT1i pretreatment before ketamine or sevoflurane exposure significantly suppressed the expression of all the tested components, NR1, NR2, RASD1, and even DMT1 (Fig

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This combination represents a holistic approach to health and one that crucially recognises the interconnected nature of our body's systems and the unique challenges women face during midlife transitions

Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)