The results showed that in the SUSTAIN 3, 7, and 10 trials, nausea/vomiting during dose escalation or throughout treatment contributed minimally ( 65 years), and baseline cardiovascular risk profile (prior myocardial infarction or stroke vs no prior MI or stroke, and established cardiovascular disease vs CV risk factors alone, including chronic kidney disease)
The average follow-up time with participants was 165 days, and slightly over 50% of participants discontinued each medication
It also significantly improved cardiometabolic parameters, including blood pressure, HbA1c, lipids, and C-reactive protein
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Some underlying medical conditions, like diabetes and hypothyroidism, may also influence how much weight you may lose