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But heres what I keep coming back to

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Depending on the infusion, some patients get an IV infusion up to twice a week

Depletion of Methylfolate Directly Another way the body breaks the peroxynitrite cycle is by directly scavenging peroxynitrite using methylfolate.34 This results in oxidized methylfolate, which cannot be used until it has been regenerated back to its original form by ascorbic acid (vitamin C).36 This is another pathway that reduces folate levels, contributing to low thymidine levels and potential DNA strand breaks

The study protocol and the subject information and the consent form were reviewed and approved by a local ethics committee according to document number 3657 (including the number and the date in 11/11/2021) to get this approval