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Rotating injection sites is recommended to avoid irritation

There is large inter-person variability in response to GLP1 medications both in terms of weight loss and side effects, with the two potentially being related (that is, people who experience more nausea may lose more weight 30 )

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If anything, the marked elevation of circulating glucagon we observed following overnight pretreatment with REMD2.59 was associated with a reduction of pancreatic glucagon content