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However, when the immune system becomes dysregulated, it can generate responses against self-antigens, leading to the attack of normal tissue cells and development of autoimmune diseases (AIDs) (6, 7)

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Ligand data set Two-dimensional (2D) structures of the used compounds are sketched in Maestro molecular modeling package of the Schrodinger.Citation22 Protonation states of studied compounds are determined and these molecules are optimized in the physiological pH using LigPrep moduleCitation23

Tyrosinase inhibition reduces the formation of unwanted pigmentation allowing for control over skin tone and brown spots

A familiar culprit This work builds on recent significant work from the Birsoy lab