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Lau and colleagues reported that these features together extend its terminal half-life in humans to roughly 165 hours

Portion Control: Semaglutide controls appetite, but mindful eating practices can further enhance its effects

92 LHeureuxMCBrubakerPL

I never lost my athlete's appetite, but I was no longer spending hours each day burning those calories off

It belongs to a wider set of peptides moving through longevity and biohacker circles, including BPC-157, Cerebrolysin, Semax, Selank, Dihexa, P21, and the neurotrophic factors BDNF and klotho, whose human cognitive evidence ranges from thin to absent and which I reviewed in detail here