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Even more, ellagic acid has additionally been shown to increase monoamine oxidase B (MAO-B), nuclear factor (erythrocyte derivation 2), Nrf2, and heme oxygenase 1 (HO-1) and reduce the loss of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra pars compacta (SNC) (Sarkaki et al., 2016)

In the cell, such a process can initiate and propagate a radical chain reaction that leads to oxidized organic products, a chemistry broadly defined as the Fenton reaction 11

In PNA mice, EBF-2 treatment (40 mg/mL for 14 days) decreased peanut sIgE and the amount of IgE-producing plasma cells, and presented clinically with complete protection from anaphylaxis and plasma histamine secretion upon peanut challenge [49]