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[76] Ruminants, such as cows and sheep, are foregut fermenters, meaning that plant food undergoes microbial fermentation in the rumen before entering the true stomach (abomasum), thus allowing them to absorb the vitamin B 12 produced by the bacteria

2019 Sep-Oct;23(5):438

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If left at room temperature for an extended period, it could lose its biological activity due to oxidation and hydrolysis, compromising the validity of experimental results

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