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Although significant knowledge gaps remain regarding the full scope of KYN metabolites, those produced downstream of KMO are generally regarded as neurotoxic and have been implicated in psychopathology

The evolutionary human diet contained roughly equal amounts of omega-6 and omega-3 fatty acids, whereas todays Western diet typically contains much more omega-6 fats

Glutathione can exist intracellularly in either an oxidized (glutathione disulfide) or reduced (glutathione) molecular state

rates of these events are comparable to other aqueous vitamin injections and rarely necessitate treatment interruption

But the details matter more than most guides let on