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Biochem J 369(3):477484 Ma Be, Chen D, Liu Y, Zhao Z, Wang J, Zhou G, Xu K, Zhu T, Wang Q, Ma C (2021) Yanghe decoction suppresses the experimental autoimmune thyroiditis in rats by improving NLRP3 inflammasome and immune dysregulation
Rights and permissions About this article Cite this article Dwivedi, D., Megha, K., Mishra, R
These findings are consistent with previous studies suggesting that Mel and GSH may prevent structural damage in ovarian histoarchitecture by suppressing oxidative stress.10,11,15-18,21,22 Both Mel and GSH are key endogenous antioxidant molecules that neutralize free radicals and preserve tissue integrity by limiting oxidative stress-induced cellular damage.30,31 It has been previously reported that platinum-based chemotherapeutic agents such as carboplatin increase intracellular ROS production, thereby triggering lipid peroxidation (as indicated by elevated MDA levels), inflammatory responses (increased TNF- and IL-6), cellular damage, and apoptosis.2,7,8 In the current study, the increased immunoreactivity of Caspase-3 and NF-B, along with significantly elevated levels of TNF- and IL-6 in the CARB group, indicate that CARB may have simultaneously activated both apoptotic and inflammatory pathways
Maintains the production of cartilage and joints, improves skin elasticity, and makes it more supple and moisturized
