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Subsequent interest in AOD-9604 has been limited to niche research areas, particularly osteoarthritis, where intra-articular injection might bypass systemic bioavailability limitations

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Vitamin D generated by lung epithelium could lead to increased expression of antimicrobial peptides (such as cathelicidin and defensin in adjacent immune cells)

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Many nootropic ingredients have mixed evidence of their benefits, with even fewer research studies outright validating their potential