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Patients on dialysis or with end-stage renal disease should not receive GLP-1 agonists without nephrology oversight

New Zepbound direct prices represent a net increase September 6, 2024 Last week, Eli Lilly announced a new direct-to-consumer pricing schedule for Zepbound, which is tirzepatide labeled for the treatment of obesity

Always verify your vials concentration (e.g., 10 mg/ml, 15 mg/ml, or 20 mg/ml) and recalculate units every time you get a new batch to ensure the correct mg dose

The approval came after clinical trials involving 3,477 patients (2,519 on Zepbound and 958 on a placebo): Patients taking 5mg of Zepbound lost 15% of their body weight (study 1) Patients taking 10mg of Zepbound lost 19.5% (study 1) and 12.8% (study 2) of their body weight Patients taking 15mg of Zepbound lost 20.9% (study 1) and 14.7% (study 2) of their body weight Patients taking the placebo lost 3.1% (study 1) and 3.2% (study 2) of their body weight Zepbound was released to market on December 5, 2023, with six available dosages available to those with a prescription: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg

Disposable plastic fluorescence cuvettes (Sarstedt, Number 67,754) were used throughout