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In rodent models, the drug consistently reduced alcohol intake across drinking behaviours and sexes, without evidence of tolerance

26 The ADA recommends monitoring HbA1c levels twice a year for patients at goal and four times a year for patients not at goal

Any deviation requires documented medical justification and direct provider supervision

It is well appreciated that excipients can alter drug release rate and/or extent of release from dosage formulations

Sun T, Xiao H-S, Zhou P-B et al (2006) Differential expression of synaptoporin and synaptophysin in primary sensory neurons and up-regulation of synaptoporin after peripheral nerve injury