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Mediolateral (ML): 2.7 mm

or symptoms of thyroid abnormalities such as a neck mass, persistent hoarseness, or difficulty swallowing

Genome-wide atlas of gene expression in the adult mouse brain

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According to the clinical expert consulted by CADTH, a substantial gain in height velocity during the first year of treatment followed by lesser but continued gains thereafter until final adult height was achieved aligns with the expected effect for patients with SPIGFD treated with mecasermin